多伦多大学（简称多大），英文University of Toronto（简称UofT或UToronto），始建于1827年，坐落在加拿大第一大城市多伦多，起源于公元1827年的国王学院（King’s College）。多大经过近二百年的蓬勃发展及本着对知识严谨考究的学术精神，已成为一所世界顶尖的公立研究型大学，同时也被公认为加拿大综合实力第一的高等教育机构。
想要出国访问学习的小伙伴看过来啦，加拿大多伦多大学在生物信息学、计算生物学、基因组学、系统生物学、机器学习正在招收访问学者、博士后！51访学网小编每周定时更新最新的访学招聘信息，感谢关注51访学。
Bioinformatics (Epigenomics) Position
University of Toronto (U of T)
Toronto, Ontario, Canada
Posted about 12 hours agoExpires on November 23, 2020
We are seeking a bioinformatics fellow to work under the direct supervision of Dr. Daniel De Carvalho at the Princess Margaret Cancer Centre – University of Toronto. Our lab is using and developing cutting edge experimental and computational methods based on Cancer epigenomics and liquid biopsy.
The selected candidate will work in projects focused on genome-wide DNA methylation data from circulating cell-free DNA in multiple cancer types and non-oncology application, such as fatty liver disease, and will work in close collaboration with wet-lab scientists and clinicians. The selected candidate will be co-supervised by Dr. Mamata Bhat, a clinician-scientist at Toronto General Hospital.
Qualifications:
•A visiting scholar or Ph.D. in Bioinformatics, computational biology, systems biology, machine learning or related areas;
•Experience in analyzing high throughput genomics and epigenomics datasets;
•proficiency in at least one programming language and knowledge of statistics;
•Demonstrated excellent publication record of scientific achievement;
•Highly motivated and self-driven.
For consideration, please send a CV and contact information for three references to: epigenome.search@gmail.com
Selected publications:
Nassiri F, Chakravarthy A, Feng S, Shen SY, Nejad R, Zuccato JA, Voisin MR, Patil V, Horbinski C, Aldape K, Zadeh G, De Carvalho DD. Detection and discrimination of intracranial tumors using plasma cell-free DNA methylomes. Nature Medicine. 2020 Jul;26(7):1044-1047.
Nuzzo PV, Berchuck JE, Korthauer K, Spisak S, Nassar AH, Abou Alaiwi S, Chakravarthy A, Shen SY, Bakouny Z, Boccardo F, Steinharter J, Bouchard G, Curran CR, Pan W, Baca SC, Seo JH, Lee GM, Michaelson MD, Chang SL, Waikar SS, Sonpavde G, Irizarry RA, Pomerantz M, De Carvalho DD, Choueiri TK, Freedman ML. Detection of renal cell carcinoma using plasma and urine cell-free DNA methylomes. Nature Medicine. 2020 Jul;26(7):1041-1043.
Shen SY, Burgener JM, Bratman SV, De Carvalho DD. Preparation of cfMeDIP-seq libraries for methylome profiling of plasma cell-free DNA. Nature Protocols. 2019 Oct;14(10):2749-2780.
Shen SY, Singhania R, Fehringer G, Chakravarthy A, Roehrl MHA, Chadwick D, Zuzarte PC, Borgida A, Wang TT, Li T, Kis O, Zhao Z, Spreafico A, Medina TDS, Wang Y, Roulois D, Ettayebi I, Chen Z, Chow S, Murphy T, Arruda A, O’Kane GM, Liu J, Mansour M, McPherson JD, O’Brien C, Leighl N, Bedard PL, Fleshner N, Liu G, Minden MD, Gallinger S, Goldenberg A, Pugh TJ, Hoffman MM, Bratman SV, Hung RJ, De Carvalho DD. Sensitive tumour detection and classification using plasma cell-free DNA methylomes. Nature. 2018 Nov;563(7732):579-583.
