哈佛大学（Harvard University），简称“哈佛”，享誉世界的私立研究型大学，著名的常春藤盟校成员，坐落于美国马萨诸塞州波士顿都市区剑桥市。是美国本土历史最悠久的高等学府，建立于1636年，最早由马萨诸塞州殖民地立法机关创建，初名“新市民学院”。

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Position available in the joint laboratory of Dr. Roland Baron and Dr. Francesca Gori (Baron-Gori lab) in the Division of Bone and Mineral Research, Department of Oral Medicine, Harvard School of Dental Medicine, Boston.

The longstanding interest of our laboratory is to understand the molecular, cellular and genetic basis of bone growth and remodeling and the regulation of skeletal homeostasis in health and disease in humans, using animal models.

The focus of this open position is to examine novel signaling mechanisms by which PTH regulates Wnt signaling, increases bone formation rate and represses bone marrow adipose tissue and its role in the anabolic action of PTH/PTHrP in bone. A separate aspect of this work is to understand the role of osteocyte biology in the responses to PTH/PTHrP.

The Baron/Gori laboratory is currently funded by three NIH institutes: NIDCR (Gori), NIDDK and NIAMS (Baron) as well as by other sources. Our laboratory aims for excellence in research and makes all efforts to publishing its work in top tier scientific and medical journals. Training of young scientists is also a key aspect of our laboratory, with a very successful history.

EDUCATION AND EXPERIENCE REQUIRED

Applicants must have a PhD degree. 

Combined MD/PhD or DDS-DMD/PhD degrees are a plus.

We seek highly motivated young scientists with strong written and oral communication skills who can work independently. 

This project involves the use of genetically engineered mice, cell and molecular biology and bioinformatic techniques, as well as culture of primary cells and cell lines. 

Commensurate with experience, first author publication(s) in top-tier bone and/or cell and molecular biology journals, expertise in signal transduction analysis, FACS analysis and/or large-scale data analysis, specifically bulk and single cell RNA-seq, will be considered a plus.

Prior experience in skeletal research in addition to the above skills is a plus but not a requirement.

APPLICATION REQUIREMENTS

To apply for this position, please email a cover letter, C.V. and three reference contacts to:

francesca_gori@hsdm.harvard.edu and roland_baron@hms.harvard.edu