We are seeking highly motivated candidates (Visiting scholar)with interests in regenerative biology to join Dr. Huang’s laboratory at UCSF
(website: http://www.cvri.ucsf.edu/~huang/lab/Research.html).
The laboratory uses the heart as a model system to investigate organ development, regeneration and repair in adult zebrafish, neonatal and adult mice,
with an emphasis on the pathways that regulate resident stem cell activation and mature cell dedifferentiation/proliferation, and with innovative and integrated approaches
in single cell analysis, advanced imaging microscopy and genome manipulation technology.
Research Directions
1, Developing novel intravital imaging in live animals and tissue clearing techniques for high- resolution visualization of cellular behavior, activity and interaction during heart development, regeneration and injury repair.
2,Performing functional screens to induce adult mouse and human cardiomyocyte regeneration using both candidate gene and directed evolution approaches integrated with CRISPR/Cas9 genome manipulation technology.
3, Taking pharmacological and genetic approaches to uncover the unifying principle governing the decline of regenerative potentials in adult mammalian organs and appendages including the heart, digit/limb, skin, brain, and spinal cord.
4, Leveraging the power of phylogenetic screen to identify novel mammalian animal models with extraordinary tissue regenerative capacity.
5, Investigating human genetic mutations and underlying molecular mechanisms in rare heart diseases that may result in preservation of cardiac regenerative potential.
We invite candidates with a highly productive training record, strong research motivation, and extensive experience in any of but not limited to the following areas: (1) developmental and regenerative biology,
(2) heart physiology and cardiomyocyte biology,
(3) cell division, signaling, and bioinformatics data analysis. Successful candidate will work in a highly interdisciplinary research program that interfaces developmental and stem cell biology, regenerative medicine, and cardiovascular diseases.
To apply, interested candidates should submit a single PDF file including
1) a cover letter with a brief statement of research experience, interest, and career plan,
2) curriculum vitae, and
3) a list of three references to Dr. Huang (Guo.Huang@ucsf.edu).
院校简介
加州大学旧金山分校(University of California, San Francisco),简称UCSF,位于美国加利福尼亚州旧金山, 美国加州大学系统的第二所公立大学,是世界著名的生命科学及医学中心。 加州大学旧金山分校的前身是1864年于旧金山建立的托兰医学院(Toland Medical College),1873年加入加州大学,成为伯克利加州大学附属的医学院,在伯克利、旧金山等地均有设点。 1952年加州大学开始体制改革后,加州大学旧金山分校逐渐成为一所独立的公立大学,学校设施均迁入旧金山。
加州大学旧金山分校是加州大学系统中唯一的只专注于健康和生命科学的大学,也是加州大学系统中唯一的只进行严格的研究生教育的大学,以医学和生命科学而闻名。 截止2018年10月,共有9位加州大学旧金山分校的教授或研究人员曾获得诺贝尔奖。 2018-19年度,在世界大学学术排名中,加州大学旧金山分校临床医学位列世界第2、生命科学位列世界第3;在US News全美最佳医院排名中,UCSF附属医院位列全美第6、美国西部第1。
2019软科世界大学学术排名(ARWU)世界第20。加州大学旧金山分校设有牙医学院、医学院、护理学院、药学院和研究生院;热门专业有医学、牙医学、护理学和生物化学等专业。
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