The Ozcan laboratory (www.ozcanlab.com) in the department of endocrinology at harvard medical school Boston children’s hospital offers postdoctoral and visiting scholar positions.

The position is offered to study the role of endoplasmic reticulum (ER) stress signaling in hypothalamic control of metabolic homeostasis, neuron activity and leptin resistance in obesity. The interested candidates can check our recent publications in this area to understand the area of research better:

Ozcan L, et al. Cell Metabolism. 2009 Jan 7;9(1):35-51. Endoplasmic reticulum stress plays a central role in development of leptin resistance.

Liu J et al., Cell. 2015 May 21;161(5):999-1011. Treatment of obesity with celastrol.

Lee J et al., Nature Medicine. 2016 Sep;22(9):1023-32. Withaferin A is a leptin sensitizer with strong antidiabetic properties in mice.

Feng X, et al., Nature Medicine. 2019 March 4-Online publication. IL1R1 is required for celastrol’s leptin-sensitization and antiobesity effects.

The ideal candidate for this position should have a Ph.D., M.D. or  or visiting scholar. degrees with strong experience in neuroscience and molecular biology evident by peer-reviewed publications in reputable journals. Candidates, who have expertise in electrophysiological recordings of neurons, stereotaxic surgeries and molecular biology with experience in obesity-related metabolic research will be given priority.

Interested candidates should forward their research interests, curriculum vitae along with the name and contact information of three referees to Dr. Umut Ozcan; e-mail: umut.ozcan@childrens.harvard.edu

波士顿儿童医院始于1869年，一家非盈利医疗机构。140年以来，一直在为儿童疾病的治疗而努力，从1947年首次成功缓解白血病到最近的复杂胎儿心脏缺陷的矫正，建树颇多。除了哈佛医学院，合作伙伴还包括哈佛干细胞研究所、麻省理工学院卫生科学与技术、博德研究所、孤独症联盟和波士顿大学。并且与丹娜法伯癌症研究院、布列根和妇女医院以及麻省总医院保持着紧密的合作关系。

波士顿儿童医院有395张床位，为21岁以下的人群提供全套的医疗服务。每年接纳的病患达到了24，943人次，228个专门临床项目计划每年接纳557，620人次；2012年手术量达到26，534台。

此外, 波士顿儿童医院是世界上最大的以儿童医院为背景的研究机构。研究团队有1100多位科学家，包括9名国家科学院人员、11名医学研究所在职人员和9名霍华休斯医学研究所人员。每年科研投入2亿2千5百万美元，多于任何一家儿童医院。波士顿儿童医院的研究人员John F. Enders为，1954年诺贝尔奖得主，脊髓灰质炎疫苗的奠基人。

波士顿儿童医院享誉全球,拥有璀璨的今天和辉煌的过去。波士顿儿童医院的出色表现不仅在于其手术创新以及新的治疗方法的发现，还在于为儿童提供高质量的医疗并给予儿童高度的关注。