克利夫兰医学中心是世界最著名医疗机构之一，机构集合医疗、研究和教育三位一体，提供专业医疗和最新治疗方案的非营利性机构。克利夫兰医学中心始建于1921年2月28日 ，隶属于俄亥俄州一家非营利性公司——克利夫兰临床基金会，并由其经营。被美国以及全世界所公认的顶级医疗中心之一，尤其是在医疗技术和医疗管理系统，以及心血管疾病治疗方面。
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· Cleveland Clinic
· Location: Cleveland, OH
· Job Number: 7068545 (Ref #: ea3ff984)
· Posting Date: Aug 4, 2020
· Application Deadline: Open Until Filled
Job Description
Immunology and Sex Steroids
Do you have a background in immunology and are interested in translational medicine? If so, a fellowship position is available in the laboratory of Dr. Nima Sharifi at the Cleveland Clinic.
We recently discovered the genetic basis for sex steroid metabolism that regulates distinct clinical immune and inflammatory response in humans (Zein, et al.PNAS. 2020; 117(4) 2187-2193).
The steroid metabolism consequences on androgen synthesis is something our group has worked out in great detail (Chang, et al.Cell. 2013;154:1074-84; Hearn, et al.Lancet Oncol. 2016;17:1435-44;JAMA Oncol. 2018;4:558-62).
We have discovered steroid metabolism drivers that dictate a general mechanism of human physiology that impinges on multiple pathophysiologic disease processes.
We are searching for an incisive and highly driven postdoctoral or visiting scholar fellow in immunology to dissect the mechanisms by which specific downstream sex steroids (i.e., androgens and estrogens) conduct the immune response.
The fellow will be embedded in a unique and multidisciplinary environment with exposure to tumor metabolism, molecular oncology, endocrine physiology, drug development and clinical trials.
Further details are available at: http://www.lerner.ccf.org/cancerbio/sharifi/
The ideal candidate has a Ph.D. degree in immunology or molecular immunology and is highly driven.
Outstanding verbal and communication skills are required. Interested candidates should send their CV and contact information for 3 references to:
Nima Sharifi, M.D.
Kendrick Family Chair for Prostate Cancer Research
Director, GU Malignancies Research Center
sharifn@ccf.org
Please send your curriculum vitae and contact information for 3 references to [Name of Contact Person]
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