瑞典KTH皇家理工学院博士后职位招聘–数据驱动建模和/或组学表征方面

Job description

The project addresses the challenge of creating and optimising a scalable stirred tank bioreactor based process for the expansion and differentiation of pluripotent stem cells. The project will explore the generation of cardiac tissue with relevance to manufacturing applications. The project will include aspects such as optimization of bioreactor process, support from process analytical technology as well as from omics characterisation.

It will be carried out at KTH in Chotteau’s group, Cell Technology group, CETEG, leader in high cell density perfusion for the production of biopharmaceuticals, in collaboration with the company AstraZeneca, Gothenburg, Sweden, within AdBIOPRO, interacting with the Centre’s academic and industrial partners. AdBIOPRO, Competence Centre for Advanced BioProduction by Continuous Processing, is an interactive Competence Center with high focus on multidisciplinary collaboration within academia and industry.

AstraZeneca Biopharmaceuticals R&D is continuing to build a new cell therapy department with the goal to establish AstraZeneca as a world-leader in the stem cell field and to build a competitive pipeline within cell therapy across disease areas within Cardiovascular, Renal and Metabolism (CVRM) and Respiratory and Inflammation (R&I). The cell therapy department will bring together >50 specialists to support the organisation with cell therapy and bioprocessing expertise and capabilities.

The new department will be an agile “biotech-like” organisation, with specialists in the department working closely with experts across AstraZeneca to bring to bear the existing and emerging platforms in stem cell technologies, new modalities, universal cell lines, and CRISPR-mediated genome editing.

AstraZeneca Gothenburg site is one of AstraZeneca’s three strategic R&D centers, Gothenburg site. With more than 2,400 employees from over than 50 countries, the vibrant Gothenburg site is a truly inspiring place to work, where the history and future of scientific breakthrough come together

What we offer 

• A position at a leading technical university that generates knowledge and skills for a sustainable future
• Engaged and ambitious colleagues along with a creative, international and dynamic working environment
• Work in Stockholm, in close proximity to nature
• The project is headed by Veronique Chotteau, Head of CETEG at Dept. Industrial Biotechnology, is the Director of AdBIOPRO and partners of several other initiatives. She has a long experience of developing biopharmaceutical drug bioprocesses for human therapy, and is leader in high cell density perfusion for the production of biopharmaceuticals. CETEG focusses on the process development for biologics, including perfusion process, process analytical technology and development of dynamic metabolism models. The project is co-supervised by Dr Michael Delahaye, Director of Cell Therapy Bioprocessing, Biopharmaceuticals R&D Cell Therapy Dept., AstraZeneca. Michael has recently joined the BioPharmaceuticals R&D Cell Therapy Department at AstraZeneca, and brings with him almost 15 years of industrial experience within the cell and gene therapy sector. His key focus is the development and delivery of robust manufacturing processes, supported by rapid, high resolution characterisation tools to facilitate the production of cell therapies.

Qualifications

Requirements

• A doctoral degree or an equivalent foreign degree. This eligibility requirement must be met no later than the time the employment decision is made.
• Research expertise
• Teaching abilities
• Collaborative abilities
• Independence
• Awareness of diversity and equal opportunity issues, with specific focus on gender equality
• Excellent aptitude to apply theoretical skill in practice
• Excellent written and oral communication skills
• A doctoral degree or an equivalent foreign degree in biotechnology, bioengineering or chemical engineering. This eligibility requirement must be met no later than the time the employment decision is made.
• Experience in bioprocessing, preferably of stem cells or of mammalian cells, is mandatory

Preferred qualifications

• A doctoral degree or an equivalent foreign degree, obtained within the last three years prior to the application deadline
• Experiences in data-driven modelling and/or in omics characterization are advantageousGreat emphasis will be placed on personal skills.

Trade union representatives

You will find contact information to trade union representatives at KTH’s webbpage.

To apply for the position 

Log into KTH’s recruitment system in order to apply for this position. You are the main responsible to ensure that your application is complete according to the ad.

Your complete application must be received at KTH no later than the last day of application, midnight CET/CEST (Central European Time/Central European Summer Time).

About the employment

The position offered is for, at the most, three years.

A position as a postdoctoral fellow is a time-limited qualified appointment focusing mainly on research, intended as a first career step after a dissertation.

Others

Striving towards gender equality, diversity and equal conditions is both a question of quality for KTH and a given part of our values.

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Disclaimer: In case of discrepancy between the Swedish original and the English translation of the job announcement, the Swedish version takes precedence.