美国康奈尔大学博士后职位招聘–细胞或分子生物学、生物化学或生物医学工程

Postdoctoral Associate position available in the Lammerding Lab 

A postdoctoral researcher position is available in the Lammerding laboratory to investigate how mechanical stimuli and deformation of the cell nucleus modulate the expression of mechanoresponsive genes and chromatin organization through an NIH funded project. The research builds on previous discoveries in the Lammerding lab that found that nuclear envelope proteins play crucial roles in the ability of cells to respond to mechanical stimuli (Lammerding et al. J Clin Invest 2004; Ho et al. Nature 2013; Kalukula et al. Nat Rev Mol Cell Biol 2022) and that cell migration through confined spaces results in nuclear envelope rupture, DNA damage, and chromatin modification (Denais et al. Science 2016; Shah et al. Current Biol 2021; Hsia et al. iScience 2022).

Additional research opportunities are available to investigate the biophysical mechanism by which cells move their large nucleus through tight spaces (see for example, Keys et al. J Cell Science 2024). The available research projects involved genomic and transcriptomic analyses, live cell imaging of cells expressing fluorescent reporters, and custom-developed devices to mimic physiological environments and mechanical stimulation.

The Lammerding laboratory is part of the Weill Institute of Cell and Molecular Biology and the Meinig School of Biomedical Engineering at Cornell University. As the home of thirteen highly interactive labs specialized on various aspects of cell biology research, the Weill Institute houses numerous state-of-art imaging, biochemical, molecular biology equipment on the central Cornell campus. Cornell provides abundant training opportunities and excellent support for postdoctoral fellows. Generous stipends and benefits will be provided, with the starting salary for recent graduates based on the NIH NRSA postdoctoral stipend levels..

Qualifications: 

• Ph.D. in cell or molecular biology, biochemistry, or biomedical engineering
• Previous experience working with mammalian cells is required.
• Experience with bioinformatics, including python, R, and linux operating system (e.g., NGS raw data read processing and downstream analysis) is desired and a considerable plus.
• Experience with cell and molecular biology techniques such as cloning, immunoblot analysis, immunofluorescence, NGS library preparation (especially RNA-seq and ATAC-seq) is strongly desired.
• Experience with fluorescence microscopy and image analysis is desired, but not required.
• Proficiency in English and a successful record of publications is required.

Application: 

Please include the following materials:

• Research statement, including a brief summary of previous research experiences, along with motivation and specific fit for the above project(s). Suggested length: 1-2 pages
• Curriculum vitae
• Names and contact information for a minimum of three references

EEO Statement:

Diversity and Inclusion are a part of Cornell University’s heritage. We are a recognized employer and educator valuing AA/EEO, and we do not tolerate discrimination based on any protected characteristic, including race, ethnic or national origin, citizenship and immigration status, color, sex/gender, pregnancy or pregnancy-related conditions, age, creed, religion, actual or perceived disability (including persons associated with such a person), arrest and/or conviction record, military or veteran status, sexual orientation, gender expression and/or identity, an individual’s genetic information, domestic violence victim status, familial status, marital status, or any other characteristic protected by applicable federal, state, or local law. We also recognize a lawful preference in employment practices for Native Americans living on or near Indian reservations in accordance with applicable law.

Cornell University embraces diversity and seeks candidates who will contribute to a climate that supports students, faculty, and staff to all identities and backgrounds. We encourage individuals from underrepresented and/or marginalized identities to apply.

Pay Range:$61,008.00 – $87,000.00

Pay Ranges:

The hiring rate of pay for the successful candidate will be determined considering the following criteria:

• Prior relevant work or industry experience.
• Education level to the extent education is relevant to the position.
• Academic Discipline (faculty pay ranges reflects 9-month annual salary)
• Unique applicable skills.